Pathology and Laboratory CPT Questions 2025

Pathology and Laboratory CPT Questions 2025 : In this article, we collect some important questions related to pathology and laboratory series guidelines. This series is very important for the Certified Professional Coder (CPC) exam, and out of total 100 questions, six come from the pathology and laboratory. Let’s Start Pathology & Laboratory Series Questions CPT.

The AAPC’s Certified Professional Coder (CPC) exam is currently the gold standard of coding certifications. Let’s take a look at this certification exam now.

1. A physician performed an automated urinalysis with microscopy. The testrevealed the presence of bacteria. The urine specimen was then cultured, and aquantitative colony count was obtained. How should you report the lab services?
a. 81001, 87086
b. 81000, 87086
c. 81002, 87086
d. 81001, 87088

2. A physician ordered a lab test to determine the amount of chloride present in two different urine specimens for the same patient. The first specimen was obtained in the morning, and the second specimen was obtained in the afternoon. How should you report these lab services?
a. 82438, 82436
b. 82438, 82436-51
c. 82436, 82436-91
d. 82438, 82728

3. In preparation for a transfusion, the lab thawed three units of fresh frozenplasma. How should you report these services?
a. 86927
b. 86930
c. 86927 x3
d. 86932

4. Cytopathology slides prepared from a cervical specimen were manually scored using the Bethesda System. Lab personnel performed the scoring under physician supervision. The results were positive. The same physician also prepared a writteninterpretation. How should you report these services?
a. 88164, 88141
b. 88165, 88141
c. 88164, 88142
d. 88165, 88142

5. In pathology, is it appropriate to append modifier 51 to the codes in case ofrepeated tests. a. True b. False6. Arielle underwent a combined rapid anterior pituitary evaluation panel with multiple exposure and suppressions and had acute hepatitis panel. How these tests should be reported.
a.82024 X4, 83002 X4, 83001 X4, 84146 X4, 83003 X4, 82533 X4, 84443 X4
b.80418, 80076
c.80418, 80074
d.80076

7. Physician orders basic and comprehensive metabolic panels with calciumionized. Select the code(s) on how this is reported.
a. 80053, 80047
b. 80053
c. 80047, 82040, 82247, 82310, 84075, 84155, 84460, 84450
d. 80053, 82330

8. Dr. Ronald, a pathologist, completed both gross and microscopic surgical pathology after lung wedge biopsy. Dr.Myth, the surgeon, sent a single specimen to the laboratory after the completion of limited biopsy by thoracotomy. How would Dr. Ronald report his service?
a. 88300, 88307
b.32151, 88305-26
c.88307
d.32098, 88307-26

9. A surgical specimen was removed from the proximal jejunum during a resectionfor adenocarcinoma and was submitted to surgical pathology for gross and microscopic examination. The correct code for this service is:
a. 88307
b. 88309
c. 88304
d. 88305

10. The physician performs the following tests on her automated equipment: HDL, total serum cholesterol, triglycerides, and a quantitative glucose. The correctcodes for these procedures are:
a. 83718, 82465, 84478, 82947
b. 83721, 82465, 82951
c. 80061, 82947
d. 80061, 82950

Pathology and Laboratory CPT Questions 2025

11. A patient with heart disease is being treated with digoxin. The physicianorders a therapeutic drug test to measure the level of digoxin. What is the correctcode?
a. 80162
b. 80163
c. 80185
d. 80184

12. A patient with depression, anxiety, bipolar disorder, and alcoholism is being treated with doxepin. The physician orders a therapeutic drug test to measure the level of doxepin. What is the correct code?
a. 80166
b. 80305
c. 80335
d. 80337

13. Dr. A, pathologist, requested Dr. B for review of patients history and medicalrecords for complex diagnostic problem clinically.
a. 80335
b. 80500
c. 80166
d. 80502

14. Dr. A, pathologist, requested to Dr. B, for reporting of test results withoutreview of patients history and medical records.
a. 80335
b. 80500
c. 80166
d. 80502

15. Storage of ovarian tissues for 5 years.
a. 89346
b. 89344
c. 89344 X4
d. 89344 X5

16. Three individual tissue specimens from a partial left breast mastectomy were submitted for surgical pathology gross and microscopic evaluation. The reason forsurgery was lesions in the breast. Each specimen required an independent comprehensive examination, report, and decalcification. Which code(s) should bereported for the laboratory services?
a. 88307 x3, 88311
b. 88307, 88331, 88323 x3
c. 88305
d. 88305, 88331, 88323 x3

17. This patient is in for a kidney biopsy (50200) because a mass was identified byultrasound. The specimen is sent to pathology for gross and microscopicexamination. Report the technical and professional components for this service:
a. 88305-26, N28.9
b. 88307-26, N28.9
c. 88307, N28.9
d. 88305, N28.9

18. CLINICAL HISTORY: Mass right atrium. SPECIMEN RECEIVED: Left atrium. GROSS DESCRIPTION: The specimen is labeled with patient’s name and left atrial Myxoma and consists of a 4 ×4 ×2 cm ovoid mass with a partially calcified hemorrhagic white tan tissue. INTRAOPERATIVE FROZEN SECTION DIAGNOSIS: Myxoma. MICROSCOPIC DESCRIPTION: Sections show a well circumscribed mass consisting of fibromyxoid tissue showing numerous vascular channels. Areas of superficial ulceration and chronic inflammatory infiltrate are noted. Areas of calcification are also present DIAGNOSIS: Myxoma, benign, left atrium.
a. 88305- 26
b. 88305-26, 88331-26, D15.1
c. 88307-26, 88331, D15.1
d. 88305-26, D15.1

19. This 69-year-old female presents to the laboratory after her physician ordered troponin, quantitative, and troponin, qualitative assay, to assist in the diagnosis of her chief complaint of acute onset of chest pain.
a. 84484, 80299, R07.2
b. 84512, 84484, 80299, R07.89
c. 84484, 84512, R07.9
d. 84484, 84466, R07.89

20. CLINICAL HISTORY: Necrotic soleus muscle, right leg. SPECIMEN RECEIVED: Soleus muscle, right leg. GROSS DESCRIPTION: Submitted in formalin, labeled with the patient’s name and soleus muscle right leg are multiple irregular fragments of tan, gray,brown soft tissue measuring 8 ×8 ×2.5 cm in aggregate. Multiple representative fragments are submitted in four cassettes. MICROSCOPIC DESCRIPTION: The slides show multiple sections of skeletal muscle showing severe coagulative and liquefactive necrosis. Patchy neutrophilic infiltrates are present within the necrotic tissue. DIAGNOSIS: Soft tissue, soleus muscle, right leg debridement; necrosis andpatchy acute inflammation, skeletal muscle, fragments of
a. 88305-26, M62.50
b. 88304-26, M60.009
c. 88307-26, I96
d. 88304-26, M62.50

ANSWERS :–

1-A ,       2-C ,       3-C ,      4-A,        5-B ,       6-C ,     7-D,      8-C,     9-B,      10-C,

11-A ,    12-C ,     13-D ,    14-B ,      15- D,      16-A ,    17-D ,    18- B,   19-C ,    20-B ,

Medical Coding Companies in Mumbai  : https://medicopediaa.com/top-medical-coding-companies-in-mumbai/

80000 Series CPT Questions:- https://medicopediaa.com/pathology-laboratory-series-questions-cpt/

In this Article We Cover All Questions Set related to Pathology & Laboratory Series Questions CPT .

CPT 8 series question pdf , 80000 series cpt questions and answers ,pathology and laboratory cpt questions and answers ,pathology and laboratory 8 series question collection, Pathology & Laboratory Series Questions CPT , Mock Set cpt 80000 series , 50 Question Set of 8 Series , CPT guidlines Chapterwise , CPT mock Set Collection, CPC Preparation Question Set  , CPC exam Question Set 2024 , 2024 Questions and Answers of CPC exam , Medical Coding CPC Exam Mock Set , Coding Guidlines Question Set, Pathology & Laboratory Series Questions CPT ,Pathology and Laboratory CPT Questions 2025………….

For Any Query : DM me on Instagram – @medico_pediaa